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Characterization of JAK1 Pseudokinase Domain in Cytokine Signaling
The Janus kinase-signal transducer and activator of transcription protein (JAK-STAT) pathway mediates essential biological functions from immune responses to haematopoiesis. Deregulated JAK-STAT signaling causes myeloproliferative neoplasms, leukaemia, and lymphomas, as well as autoimmune diseases....
Autores principales: | Raivola, Juuli, Haikarainen, Teemu, Silvennoinen, Olli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016850/ https://www.ncbi.nlm.nih.gov/pubmed/31892268 http://dx.doi.org/10.3390/cancers12010078 |
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