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Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy

Histone deacetylation inhibitors (HDACi) offer high potential for future cancer therapy as they can re-establish the expression of epigenetically silenced cell death programs. HDACi-induced autophagy offers the possibility to counteract the frequently present apoptosis-resistance as well as stress c...

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Detalles Bibliográficos
Autores principales: Mrakovcic, Maria, Fröhlich, Leopold F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016854/
https://www.ncbi.nlm.nih.gov/pubmed/31906235
http://dx.doi.org/10.3390/cancers12010109