Loss of Rb1 Enhances Glycolytic Metabolism in Kras-Driven Lung Tumors In Vivo

Dysregulated metabolism is a hallmark of cancer cells and is driven in part by specific genetic alterations in various oncogenes or tumor suppressors. The retinoblastoma protein (pRb) is a tumor suppressor that canonically regulates cell cycle progression; however, recent studies have highlighted a...

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Detalles Bibliográficos
Autores principales: Conroy, Lindsey R., Dougherty, Susan, Kruer, Traci, Metcalf, Stephanie, Lorkiewicz, Pawel, He, Liqing, Yin, Xinmin, Zhang, Xiang, Arumugam, Sengodagounder, Young, Lyndsay E.A., Sun, Ramon C., Clem, Brian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016860/
https://www.ncbi.nlm.nih.gov/pubmed/31963621
http://dx.doi.org/10.3390/cancers12010237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016860/
https://www.ncbi.nlm.nih.gov/pubmed/31963621
http://dx.doi.org/10.3390/cancers12010237

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