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Deregulating the CYP2C19/Epoxy-Eicosatrienoic Acid-Associated FABP4/FABP5 Signaling Network as a Therapeutic Approach for Metastatic Triple-Negative Breast Cancer

Recurrence and metastasis are the main causes of triple-negative breast cancer (TNBC) mortality. On the basis of our clinical cohorts and integrative omics analyses, we hypothesized that understanding the interplay between fatty acid binding protein (FABP) and epoxy-eicosatrienoic acid (EET) driven...

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Detalles Bibliográficos
Autores principales: Apaya, Maria Karmella, Hsiao, Pei-Wen, Yang, Yu-Chih, Shyur, Lie-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016875/
https://www.ncbi.nlm.nih.gov/pubmed/31941087
http://dx.doi.org/10.3390/cancers12010199