HIF1α/TET1 Pathway Mediates Hypoxia-Induced Adipocytokine Promoter Hypomethylation in Human Adipocytes

Obesity is associated with the accumulation of dysfunctional adipose tissue that secretes several pro-inflammatory cytokines (adipocytokines). Recent studies have presented evidence that adipose tissues in obese individuals and animal models are hypoxic, which may result in upregulation and stabiliz...

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Detalles Bibliográficos
Autores principales: Ali, Mohamed M., Phillips, Shane A., Mahmoud, Abeer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016890/
https://www.ncbi.nlm.nih.gov/pubmed/31935962
http://dx.doi.org/10.3390/cells9010134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016890/
https://www.ncbi.nlm.nih.gov/pubmed/31935962
http://dx.doi.org/10.3390/cells9010134

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