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Computational Analysis of Crystallization Additives for the Identification of New Allosteric Sites
[Image: see text] Allosteric effect can modulate the biological activity of a protein. Thus, the discovery of new allosteric sites is very attractive for designing new modulators or inhibitors. Here, we propose an innovative way to identify allosteric sites, based on crystallization additives (CA),...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016913/ https://www.ncbi.nlm.nih.gov/pubmed/32064372 http://dx.doi.org/10.1021/acsomega.9b02697 |