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Inhibition of Rho-Associated Kinase Suppresses Medulloblastoma Growth

Medulloblastoma is one of the most common malignant brain tumor types in children, with an overall survival of 70%. Mortality is associated with metastatic relapsed tumors. Rho-associated kinases (ROCKs), important for epithelial-mesenchymal transition (EMT) and proper nervous system development, ha...

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Detalles Bibliográficos
Autores principales: Dyberg, Cecilia, Andonova, Teodora, Olsen, Thale Kristin, Brodin, Bertha, Kool, Marcel, Kogner, Per, Johnsen, John Inge, Wickström, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016943/
https://www.ncbi.nlm.nih.gov/pubmed/31888022
http://dx.doi.org/10.3390/cancers12010073