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Epigenetic Silencing of Ubiquitin Specific Protease 4 by Snail1 Contributes to Macrophage-Dependent Inflammation and Therapeutic Resistance in Lung Cancer

There is a positive feedback loop driving tumorigenesis and tumor growth through coordinated regulation of epigenetics, inflammation, and stemness. Nevertheless, the molecular mechanism linking these processes is not well understood. In this study, we analyzed the correlation of de-ubiquitinases (DU...

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Detalles Bibliográficos
Autores principales: Lai, Chao-Yang, Yeh, Da-Wei, Lu, Chih-Hao, Liu, Yi-Ling, Chuang, Yu-Chen, Ruan, Jhen-Wei, Kao, Cheng-Yuan, Huang, Li-Rung, Chuang, Tsung-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016945/
https://www.ncbi.nlm.nih.gov/pubmed/31936290
http://dx.doi.org/10.3390/cancers12010148