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Direct Activation of TRPC3 Channels by the Antimalarial Agent Artemisinin

(1) Background: Members of the TRPC3/TRPC6/TRPC7 subfamily of canonical transient receptor potential (TRP) channels share an amino acid similarity of more than 80% and can form heteromeric channel complexes. They are directly gated by diacylglycerols in a protein kinase C-independent manner. To asse...

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Detalles Bibliográficos
Autores principales: Urban, Nicole, Schaefer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016953/
https://www.ncbi.nlm.nih.gov/pubmed/31947602
http://dx.doi.org/10.3390/cells9010202