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Pharmacological Inhibition of Oncogenic STAT3 and STAT5 Signaling in Hematopoietic Cancers

Signal Transducer and Activator of Transcription (STAT) 3 and 5 are important effectors of cellular transformation, and aberrant STAT3 and STAT5 signaling have been demonstrated in hematopoietic cancers. STAT3 and STAT5 are common targets for different tyrosine kinase oncogenes (TKOs). In addition,...

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Detalles Bibliográficos
Autores principales: Brachet-Botineau, Marie, Polomski, Marion, Neubauer, Heidi A., Juen, Ludovic, Hédou, Damien, Viaud-Massuard, Marie-Claude, Prié, Gildas, Gouilleux, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016966/
https://www.ncbi.nlm.nih.gov/pubmed/31963765
http://dx.doi.org/10.3390/cancers12010240