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Autotaxin Implication in Cancer Metastasis and Autoimunne Disorders: Functional Implication of Binding Autotaxin to the Cell Surface

Autotaxin (ATX) is an exoenzyme which, due to its unique lysophospholipase D activity, is responsible for the synthesis of lysophosphatidic acid (LPA). ATX activity is responsible for the concentration of LPA in the blood. ATX expression is increased in various types of cancers, including breast can...

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Detalles Bibliográficos
Autores principales: Peyruchaud, Olivier, Saier, Lou, Leblanc, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016970/
https://www.ncbi.nlm.nih.gov/pubmed/31906151
http://dx.doi.org/10.3390/cancers12010105