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Degradation of the Tumor Suppressor PDCD4 Is Impaired by the Suppression of p62/SQSTM1 and Autophagy

PDCD4 (programmed cell death 4) is a tumor suppressor that plays a crucial role in multiple cellular functions, such as the control of protein synthesis and transcriptional control of some genes, the inhibition of cancer invasion and metastasis. The expression of this protein is controlled by synthe...

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Detalles Bibliográficos
Autores principales: Manirujjaman, M., Ozaki, Iwata, Murata, Yuzo, Guo, Jing, Xia, Jinghe, Nishioka, Kenichi, Perveen, Rasheda, Takahashi, Hirokazu, Anzai, Keizo, Matsuhashi, Sachiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016974/
https://www.ncbi.nlm.nih.gov/pubmed/31952347
http://dx.doi.org/10.3390/cells9010218