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Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells

Platinum-based chemotherapy is the therapy of choice for epithelial ovarian cancer (EOC). Acquired resistance to platinum (PT) is a frequent event that leads to disease progression and predicts poor prognosis. To understand possible mechanisms underlying acquired PT-resistance, we have recently gene...

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Detalles Bibliográficos
Autores principales: Lorenzon, Ilaria, Pellarin, Ilenia, Pellizzari, Ilenia, D’Andrea, Sara, Belletti, Barbara, Sonego, Maura, Baldassarre, Gustavo, Schiappacassi, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016977/
https://www.ncbi.nlm.nih.gov/pubmed/31877751
http://dx.doi.org/10.3390/cells9010036