Cargando…

Oncogenic K-ras Induces Mitochondrial OPA3 Expression to Promote Energy Metabolism in Pancreatic Cancer Cells

K-ras (Kirsten ras GTPase) mutations are oncogenic events frequently observed in many cancer types especially in pancreatic cancer. Although mitochondrial dysfunction has been associated with K-ras mutation, the molecular mechanisms by which K-ras impacts mitochondria and maintains metabolic homeost...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Ning, Glorieux, Christophe, Zhang, Yanyu, Liang, Liyun, Zeng, Peiting, Lu, Wenhua, Huang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016999/
https://www.ncbi.nlm.nih.gov/pubmed/31881642
http://dx.doi.org/10.3390/cancers12010065