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The Long Non-Coding RNA Prader Willi/Angelman Region RNA5 (PAR5) Is Downregulated in Anaplastic Thyroid Carcinomas Where It Acts as a Tumor Suppressor by Reducing EZH2 Activity

Anaplastic thyroid carcinoma (ATC) represents one the most aggressive neoplasias in humans, and, nowadays, limited advances have been made to extend the survival and reduce the mortality of ATC. Thus, the identification of molecular mechanism underlying its progression is needed. Here, we evaluated...

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Detalles Bibliográficos
Autores principales: Pellecchia, Simona, Sepe, Romina, Decaussin-Petrucci, Myriam, Ivan, Cristina, Shimizu, Masayoshi, Coppola, Carmela, Testa, Domenico, Calin, George Adrian, Fusco, Alfredo, Pallante, Pierlorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017000/
https://www.ncbi.nlm.nih.gov/pubmed/31963578
http://dx.doi.org/10.3390/cancers12010235