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Pervasive Strong Selection at the Level of Codon Usage Bias in Drosophila melanogaster

Codon usage bias (CUB), where certain codons are used more frequently than expected by chance, is a ubiquitous phenomenon and occurs across the tree of life. The dominant paradigm is that the proportion of preferred codons is set by weak selection. While experimental changes in codon usage have at t...

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Detalles Bibliográficos
Autores principales: Machado, Heather E., Lawrie, David S., Petrov, Dmitri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017021/
https://www.ncbi.nlm.nih.gov/pubmed/31871131
http://dx.doi.org/10.1534/genetics.119.302542