pH-Dependent Aggregation in Intrinsically Disordered Proteins Is Determined by Charge and Lipophilicity

Protein aggregation is associated with an increasing number of human disorders and premature aging. Moreover, it is a central concern in the manufacturing of recombinant proteins for biotechnological and therapeutic applications. Nevertheless, the unique architecture of protein aggregates is also ex...

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Detalles Bibliográficos
Autores principales: Santos, Jaime, Iglesias, Valentín, Santos-Suárez, Juan, Mangiagalli, Marco, Brocca, Stefania, Pallarès, Irantzu, Ventura, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017033/
https://www.ncbi.nlm.nih.gov/pubmed/31936201
http://dx.doi.org/10.3390/cells9010145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017033/
https://www.ncbi.nlm.nih.gov/pubmed/31936201
http://dx.doi.org/10.3390/cells9010145

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