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Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN)

Translation is spatiotemporally regulated and endoplasmic reticulum (ER)-associated mRNAs are generally in efficient translation. It is unclear whether the ER-associated mRNAs are deadenylated or degraded on the ER surface in situ or in the cytosol. Here, we showed that ER possessed active deadenyla...

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Detalles Bibliográficos
Autores principales: Duan, Tian-Li, Jiao, Han, He, Guang-Jun, Yan, Yong-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017053/
https://www.ncbi.nlm.nih.gov/pubmed/31936572
http://dx.doi.org/10.3390/cells9010162