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Targeting the Sphingolipid System as a Therapeutic Direction for Glioblastoma

Glioblastoma (GBM) is the most commonly diagnosed malignant brain tumor in adults. The prognosis for patients with GBM remains poor and largely unchanged over the last 30 years, due to the limitations of existing therapies. Thus, new therapeutic approaches are desperately required. Sphingolipids are...

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Detalles Bibliográficos
Autores principales: Tea, Melinda N., Poonnoose, Santosh I., Pitson, Stuart M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017054/
https://www.ncbi.nlm.nih.gov/pubmed/31906280
http://dx.doi.org/10.3390/cancers12010111