Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells

Mutations in the gene encoding the digestive enzyme carboxyl ester lipase (CEL) are linked to pancreatic disease. The CEL variant denoted CEL-HYB predisposes to chronic pancreatitis, whereas the CEL-MODY variant causes MODY8, an inherited disorder of endocrine and exocrine pancreatic dysfunction. Bo...

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Detalles Bibliográficos
Autores principales: Dalva, Monica, Lavik, Ida K., El Jellas, Khadija, Gravdal, Anny, Lugea, Aurelia, Pandol, Stephen J., Njølstad, Pål R., Waldron, Richard T., Fjeld, Karianne, Johansson, Bente B., Molven, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017060/
https://www.ncbi.nlm.nih.gov/pubmed/31963687
http://dx.doi.org/10.3390/cells9010244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017060/
https://www.ncbi.nlm.nih.gov/pubmed/31963687
http://dx.doi.org/10.3390/cells9010244

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