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DKK1 Induced by 1,25D3 Is Required for the Mineralization of Osteoblasts

1α,25-dihydroxyvitamin D3 (1,25D3), the most popular drug for osteoporosis treatment, drives osteoblast differentiation and bone mineralization. Wnt/β-catenin signaling is involved in commitment and differentiation of osteoblasts, but the role of the Dickkopf-related protein 1 (DKK1), a Wnt antagoni...

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Detalles Bibliográficos
Autores principales: Jo, Sungsin, Yoon, Subin, Lee, So Young, Kim, So Yeon, Park, Hyosun, Han, Jinil, Choi, Sung Hoon, Han, Joong-Soo, Yang, Jae-Hyuk, Kim, Tae-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017072/
https://www.ncbi.nlm.nih.gov/pubmed/31963554
http://dx.doi.org/10.3390/cells9010236