VAPB ER-Aggregates, A Possible New Biomarker in ALS Pathology

A point mutation (P56S) in the gene-encoding vesicle-associated membrane-protein-associated protein B (VAPB) leads to an autosomal-dominant form of amyotrophic lateral sclerosis (ALS), classified as ALS-8. The mutant VAPB is characterized by ER-associated aggregates that lead to a complete reorganiz...

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Detalles Bibliográficos
Autores principales: Cadoni, Maria Piera L, Biggio, Maria Luigia, Arru, Giannina, Secchi, Giannina, Orrù, Nicola, Clemente, Maria Grazia, Sechi, GianPietro, Yamoah, Alfred, Tripathi, Priyanka, Orrù, Sandro, Manetti, Roberto, Galleri, Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017080/
https://www.ncbi.nlm.nih.gov/pubmed/31936602
http://dx.doi.org/10.3390/cells9010164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017080/
https://www.ncbi.nlm.nih.gov/pubmed/31936602
http://dx.doi.org/10.3390/cells9010164

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