Methylglyoxal-Dependent Glycative Stress and Deregulation of SIRT1 Functional Network in the Ovary of PCOS Mice

Advanced glycation end-products (AGEs) are involved in the pathogenesis and consequences of polycystic ovary syndrome (PCOS), a complex metabolic disorder associated with female infertility. The most powerful AGE precursor is methylglyoxal (MG), a byproduct of glycolysis, that is detoxified by the g...

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Detalles Bibliográficos
Autores principales: Di Emidio, Giovanna, Placidi, Martina, Rea, Francesco, Rossi, Giulia, Falone, Stefano, Cristiano, Loredana, Nottola, Stefania, D’Alessandro, Anna Maria, Amicarelli, Fernanda, Palmerini, Maria Grazia, Tatone, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017084/
https://www.ncbi.nlm.nih.gov/pubmed/31947651
http://dx.doi.org/10.3390/cells9010209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017084/
https://www.ncbi.nlm.nih.gov/pubmed/31947651
http://dx.doi.org/10.3390/cells9010209

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