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Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells

The transcription factor FOXO3 is associated with poor outcome in high-stage neuroblastoma (NB), as it facilitates chemoprotection and tumor angiogenesis. In other tumor entities, FOXO3 stimulates metastasis formation, one of the biggest challenges in the treatment of aggressive NB. However, the imp...

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Detalles Bibliográficos
Autores principales: Salcher, Stefan, Spoden, Gilles, Huber, Julia M., Golderer, Georg, Lindner, Herbert, Ausserlechner, Michael J., Kiechl-Kohlendorfer, Ursula, Geiger, Kathrin, Obexer, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017090/
https://www.ncbi.nlm.nih.gov/pubmed/31861249
http://dx.doi.org/10.3390/cells9010001