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Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells
The transcription factor FOXO3 is associated with poor outcome in high-stage neuroblastoma (NB), as it facilitates chemoprotection and tumor angiogenesis. In other tumor entities, FOXO3 stimulates metastasis formation, one of the biggest challenges in the treatment of aggressive NB. However, the imp...
Autores principales: | Salcher, Stefan, Spoden, Gilles, Huber, Julia M., Golderer, Georg, Lindner, Herbert, Ausserlechner, Michael J., Kiechl-Kohlendorfer, Ursula, Geiger, Kathrin, Obexer, Petra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017090/ https://www.ncbi.nlm.nih.gov/pubmed/31861249 http://dx.doi.org/10.3390/cells9010001 |
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