Phosphoenolpyruvate from Glycolysis and PEPCK Regulate Cancer Cell Fate by Altering Cytosolic Ca(2+)

Changes in phosphoenolpyruvate (PEP) concentrations secondary to variations in glucose availability can regulate calcium signaling in T cells as this metabolite potently inhibits the sarcoplasmic reticulum Ca(2+)/ATPase pump (SERCA). This regulation is critical to assert immune activation in the tum...

Descripción completa

Detalles Bibliográficos
Autores principales: Moreno-Felici, Juan, Hyroššová, Petra, Aragó, Marc, Rodríguez-Arévalo, Sergio, García-Rovés, Pablo M., Escolano, Carmen, Perales, Jose C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017135/
https://www.ncbi.nlm.nih.gov/pubmed/31861674
http://dx.doi.org/10.3390/cells9010018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017135/
https://www.ncbi.nlm.nih.gov/pubmed/31861674
http://dx.doi.org/10.3390/cells9010018

Ejemplares similares