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Clustered DNA Double-Strand Breaks: Biological Effects and Relevance to Cancer Radiotherapy

Cells manage to survive, thrive, and divide with high accuracy despite the constant threat of DNA damage. Cells have evolved with several systems that efficiently repair spontaneous, isolated DNA lesions with a high degree of accuracy. Ionizing radiation and a few radiomimetic chemicals can produce...

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Detalles Bibliográficos
Autores principales: Nickoloff, Jac A., Sharma, Neelam, Taylor, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017136/
https://www.ncbi.nlm.nih.gov/pubmed/31952359
http://dx.doi.org/10.3390/genes11010099