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Ubiquitin-Specific Protease 21 Promotes Colorectal Cancer Metastasis by Acting as a Fra-1 Deubiquitinase

Fos-related-antigen-1 (Fra-1), a member of the activator protein-1 (AP-1) transcription factor superfamily, has an essential role in cancer progress and metastasis and Fra-1 is considered a therapeutic target in metastatic cancer including metastatic colorectal cancer (mCRC). However, its regulation...

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Detalles Bibliográficos
Autores principales: Yun, Sun-Il, Hong, Hye Kyung, Yeo, So-Young, Kim, Seok-Hyung, Cho, Yong Beom, Kim, Kyeong Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017141/
https://www.ncbi.nlm.nih.gov/pubmed/31947604
http://dx.doi.org/10.3390/cancers12010207