Cargando…

Ubiquitin-Specific Protease 21 Promotes Colorectal Cancer Metastasis by Acting as a Fra-1 Deubiquitinase

Fos-related-antigen-1 (Fra-1), a member of the activator protein-1 (AP-1) transcription factor superfamily, has an essential role in cancer progress and metastasis and Fra-1 is considered a therapeutic target in metastatic cancer including metastatic colorectal cancer (mCRC). However, its regulation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yun, Sun-Il, Hong, Hye Kyung, Yeo, So-Young, Kim, Seok-Hyung, Cho, Yong Beom, Kim, Kyeong Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017141/ https://www.ncbi.nlm.nih.gov/pubmed/31947604 http://dx.doi.org/10.3390/cancers12010207

Ejemplares similares

The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors
por: Grou, Cláudia P., et al.
Publicado: (2015)

Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1
por: Lin, Zhenghong, et al.
Publicado: (2015)

Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis
por: Kaushal, Kamini, et al.
Publicado: (2022)

Turnip yellow mosaic virus protease binds ubiquitin suboptimally to fine-tune its deubiquitinase activity
por: Fieulaine, Sonia, et al.
Publicado: (2020)

Deubiquitinase Ubiquitin‐Specific Protease 10 Deficiency Regulates Sirt6 signaling and Exacerbates Cardiac Hypertrophy
por: Zhang, Dian‐Hong, et al.
Publicado: (2020)

To FRA or not to FRA: What is the question for science education?
por: Dagher, Zoubeida R., et al.
Publicado: (2023)

Activity-Based Ubiquitin Probes for Investigation of Deubiquitinases
por: Gui, Weijun, et al.
Publicado: (2020)

USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase
por: Fan, Yihui, et al.
Publicado: (2014)

Fra-1 Expression in Malignant and Benign Thyroid Tumor
por: Kim, Yong-Hyun, et al.
Publicado: (2001)

FRA 2005
Publicado: (2007)

Fra Angelico /
por: Angelico, fra, ca. 1400-1455
Publicado: (1992)

Cocrystallization of ubiquitin–deubiquitinase complexes through disulfide linkage
por: Negron Teron, Kristos I., et al.
Publicado: (2023)

Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor
por: Liao, Yuning, et al.
Publicado: (2017)

Structural insights into ubiquitin chain cleavage by Legionella ovarian tumor deubiquitinases
por: Kang, Sangwoo, et al.
Publicado: (2023)

Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival
por: Iskit, Sedef, et al.
Publicado: (2015)

FRA-1 as a Regulator of EMT and Metastasis in Breast Cancer
por: Casalino, Laura, et al.
Publicado: (2023)

Ubiquitin-specific protease 4 controls metastatic potential through β-catenin stabilization in brain metastatic lung adenocarcinoma
por: Hwang, Su Jin, et al.
Publicado: (2016)

Fra Diavolo opera /
por: Auber, D. F. E. (Daniel François Esprit), 1782-1871
Publicado: (1890)

Genome-Wide CRISPR/Cas9-Based Screening for Deubiquitinase Subfamily Identifies Ubiquitin-Specific Protease 11 as a Novel Regulator of Osteogenic Differentiation
por: Kaushal, Kamini, et al.
Publicado: (2022)

Deubiquitinase ubiquitin‐specific protease 9X regulates the stability and function of E3 ubiquitin ligase ring finger protein 115 in breast cancer cells
por: Lu, Qin, et al.
Publicado: (2019)

The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells
por: Wang, Xin, et al.
Publicado: (2016)

Expression and Regulation of Deubiquitinase-Resistant, Unanchored Ubiquitin Chains in Drosophila
por: Blount, Jessica R., et al.
Publicado: (2018)

A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination
por: Qiu, Jiazhang, et al.
Publicado: (2017)

Targeting E3 Ubiquitin Ligases and Deubiquitinases in Ciliopathy and Cancer
por: Shiromizu, Takashi, et al.
Publicado: (2020)

E3 ubiquitin ligases and deubiquitinases as modulators of TRAIL-mediated extrinsic apoptotic signaling pathway
por: Woo, Seon Min, et al.
Publicado: (2019)

Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases
por: Zhao, Zhou, et al.
Publicado: (2023)

Corrigendum: The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells
por: Wang, Xin, et al.
Publicado: (2016)

Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3
por: Park, Joon Kyu, et al.
Publicado: (2016)

Ubiquitin Linkage Specificity of Deubiquitinases Determines Cyclophilin Nuclear Localization and Degradation
por: Li, Yanchang, et al.
Publicado: (2020)

Deubiquitinase USP7 regulates Drosophila aging through ubiquitination and autophagy
por: Cui, Lang, et al.
Publicado: (2020)

Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection
por: Shin, Donghyuk, et al.
Publicado: (2020)

A mobile loop near the active site acts as a switch between the dual activities of a viral protease/deubiquitinase
por: Jupin, Isabelle, et al.
Publicado: (2017)

Seneca Valley Virus 3C protease negatively regulates the type I interferon pathway by acting as a viral deubiquitinase
por: Xue, Qiao, et al.
Publicado: (2018)

Deubiquitinases in Cancers: Aspects of Proliferation, Metastasis, and Apoptosis
por: LIU, Jiaqi, et al.
Publicado: (2022)

Ubiquitin-specific protease 21 stabilizes BRCA2 to control DNA repair and tumor growth
por: Liu, Jinping, et al.
Publicado: (2017)

Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes
por: Liu, Shuxin, et al.
Publicado: (2020)

Sabotage fra tidsrejsende fjerkræ
Publicado: (2009)

The linear ubiquitin-specific deubiquitinase Gumby/Fam105b regulates angiogenesis
por: Rivkin, Elena, et al.
Publicado: (2013)

Total chemical synthesis of ester-linked ubiquitinated proteins unravels their behavior with deubiquitinases
por: Sun, Hao, et al.
Publicado: (2018)

Specific targeting of the deubiquitinase and E3 ligase families with engineered ubiquitin variants
por: Gorelik, Maryna, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gadaqjn3js49brc9a94em5l0ta