Heat Shock Protein 90 Chaperone Regulates the E3 Ubiquitin-Ligase Hakai Protein Stability

The E3 ubiquitin-ligase Hakai binds to several tyrosine-phosphorylated Src substrates, including the hallmark of the epithelial-to-mesenchymal transition E-cadherin, and signals for degradation of its specific targets. Hakai is highly expressed in several human cancers, including colon cancer, and i...

Descripción completa

Detalles Bibliográficos
Autores principales: Díaz-Díaz, Andrea, Roca-Lema, Daniel, Casas-Pais, Alba, Romay, Gabriela, Colombo, Giovanni, Concha, Ángel, Graña, Begoña, Figueroa, Angélica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017148/
https://www.ncbi.nlm.nih.gov/pubmed/31952268
http://dx.doi.org/10.3390/cancers12010215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017148/
https://www.ncbi.nlm.nih.gov/pubmed/31952268
http://dx.doi.org/10.3390/cancers12010215

Ejemplares similares