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Heat Shock Protein 90 Chaperone Regulates the E3 Ubiquitin-Ligase Hakai Protein Stability

The E3 ubiquitin-ligase Hakai binds to several tyrosine-phosphorylated Src substrates, including the hallmark of the epithelial-to-mesenchymal transition E-cadherin, and signals for degradation of its specific targets. Hakai is highly expressed in several human cancers, including colon cancer, and i...

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Detalles Bibliográficos
Autores principales:	Díaz-Díaz, Andrea, Roca-Lema, Daniel, Casas-Pais, Alba, Romay, Gabriela, Colombo, Giovanni, Concha, Ángel, Graña, Begoña, Figueroa, Angélica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017148/ https://www.ncbi.nlm.nih.gov/pubmed/31952268 http://dx.doi.org/10.3390/cancers12010215

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