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CD163(+) tumor‐associated macrophage accumulation in breast cancer patients reflects both local differentiation signals and systemic skewing of monocytes

OBJECTIVES: The accumulation of tumor‐associated macrophages (TAMs) is correlated with poor clinical outcome, but the mechanisms governing their differentiation from circulating monocytes remain unclear in humans. METHODS: Using multicolor flow cytometry, we evaluated TAMs phenotype in 93 breast can...

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Detalles Bibliográficos
Autores principales: Ramos, Rodrigo Nalio, Rodriguez, Céline, Hubert, Margaux, Ardin, Maude, Treilleux, Isabelle, Ries, Carola H, Lavergne, Emilie, Chabaud, Sylvie, Colombe, Amélie, Trédan, Olivier, Guedes, Henrique Gomes, Laginha, Fábio, Richer, Wilfrid, Piaggio, Eliane, Barbuto, José Alexandre M, Caux, Christophe, Ménétrier‐Caux, Christine, Bendriss‐Vermare, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017151/
https://www.ncbi.nlm.nih.gov/pubmed/32082570
http://dx.doi.org/10.1002/cti2.1108