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CD163(+) tumor‐associated macrophage accumulation in breast cancer patients reflects both local differentiation signals and systemic skewing of monocytes
OBJECTIVES: The accumulation of tumor‐associated macrophages (TAMs) is correlated with poor clinical outcome, but the mechanisms governing their differentiation from circulating monocytes remain unclear in humans. METHODS: Using multicolor flow cytometry, we evaluated TAMs phenotype in 93 breast can...
Autores principales: | Ramos, Rodrigo Nalio, Rodriguez, Céline, Hubert, Margaux, Ardin, Maude, Treilleux, Isabelle, Ries, Carola H, Lavergne, Emilie, Chabaud, Sylvie, Colombe, Amélie, Trédan, Olivier, Guedes, Henrique Gomes, Laginha, Fábio, Richer, Wilfrid, Piaggio, Eliane, Barbuto, José Alexandre M, Caux, Christophe, Ménétrier‐Caux, Christine, Bendriss‐Vermare, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017151/ https://www.ncbi.nlm.nih.gov/pubmed/32082570 http://dx.doi.org/10.1002/cti2.1108 |
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