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DAF-16/FoxO in Caenorhabditis elegans and Its Role in Metabolic Remodeling

DAF-16, the only forkhead box transcription factors class O (FoxO) homolog in Caenorhabditis elegans, integrates signals from upstream pathways to elicit transcriptional changes in many genes involved in aging, development, stress, metabolism, and immunity. The major regulator of DAF-16 activity is...

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Detalles Bibliográficos
Autores principales: Zečić, Aleksandra, Braeckman, Bart P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017163/
https://www.ncbi.nlm.nih.gov/pubmed/31906434
http://dx.doi.org/10.3390/cells9010109