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Overexpression of Mitochondrial IF1 Prevents Metastatic Disease of Colorectal Cancer by Enhancing Anoikis and Tumor Infiltration of NK Cells

Increasing evidences show that the ATPase Inhibitory Factor 1 (IF1), the physiological inhibitor of the ATP synthase, is overexpressed in a large number of carcinomas contributing to metabolic reprogramming and cancer progression. Herein, we show that in contrast to the findings in other carcinomas,...

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Detalles Bibliográficos
Autores principales: González-Llorente, Lucía, Santacatterina, Fulvio, García-Aguilar, Ana, Nuevo-Tapioles, Cristina, González-García, Sara, Tirpakova, Zuzana, Toribio, María Luisa, Cuezva, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017164/
https://www.ncbi.nlm.nih.gov/pubmed/31861681
http://dx.doi.org/10.3390/cancers12010022