TYK2 in Tumor Immunosurveillance

We review the history of the tyrosine kinase 2 (TYK2) as the founding member of the Janus kinase (JAK) family and outline its structure-function relation. Gene-targeted mice and hereditary defects of TYK2 in men have established the biological and pathological functions of TYK2 in innate and adaptiv...

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Detalles Bibliográficos
Autores principales: Karjalainen, Anzhelika, Shoebridge, Stephen, Krunic, Milica, Simonović, Natalija, Tebb, Graham, Macho-Maschler, Sabine, Strobl, Birgit, Müller, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017180/
https://www.ncbi.nlm.nih.gov/pubmed/31936322
http://dx.doi.org/10.3390/cancers12010150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017180/
https://www.ncbi.nlm.nih.gov/pubmed/31936322
http://dx.doi.org/10.3390/cancers12010150

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