Discovery and Preliminary Characterization of Translational Modulators that Impair the Binding of eIF6 to 60S Ribosomal Subunits

Eukaryotic initiation factor 6 (eIF6) is necessary for the nucleolar biogenesis of 60S ribosomes. However, most of eIF6 resides in the cytoplasm, where it acts as an initiation factor. eIF6 is necessary for maximal protein synthesis downstream of growth factor stimulation. eIF6 is an antiassociation...

Descripción completa

Detalles Bibliográficos
Autores principales: Pesce, Elisa, Miluzio, Annarita, Turcano, Lorenzo, Minici, Claudia, Cirino, Delia, Calamita, Piera, Manfrini, Nicola, Oliveto, Stefania, Ricciardi, Sara, Grifantini, Renata, Degano, Massimo, Bresciani, Alberto, Biffo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017188/
https://www.ncbi.nlm.nih.gov/pubmed/31936702
http://dx.doi.org/10.3390/cells9010172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017188/
https://www.ncbi.nlm.nih.gov/pubmed/31936702
http://dx.doi.org/10.3390/cells9010172

Ejemplares similares