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Integrated Analysis of Structural Variation and RNA Expression of FGFR2 and Its Splicing Modulator ESRP1 Highlight the ESRP1(amp)-FGFR2(norm)-FGFR2-IIIc(high) Axis in Diffuse Gastric Cancer

Gastric Cancer (GC) is one of the most common and deadliest types of cancer in the world. To improve GC prognosis, increasing efforts are being made to develop new targeted therapies. Although FGFR2 genetic amplification and protein overexpression in GC have been targeted in clinical trials, so far...

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Detalles Bibliográficos
Autores principales: Teles, Sara Pinto, Oliveira, Patrícia, Ferreira, Marta, Carvalho, Joana, Ferreira, Pedro, Oliveira, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017189/
https://www.ncbi.nlm.nih.gov/pubmed/31881796
http://dx.doi.org/10.3390/cancers12010070