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Consensify: A Method for Generating Pseudohaploid Genome Sequences from Palaeogenomic Datasets with Reduced Error Rates

A standard practise in palaeogenome analysis is the conversion of mapped short read data into pseudohaploid sequences, frequently by selecting a single high-quality nucleotide at random from the stack of mapped reads. This controls for biases due to differential sequencing coverage, but it does not...

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Detalles Bibliográficos
Autores principales: Barlow, Axel, Hartmann, Stefanie, Gonzalez, Javier, Hofreiter, Michael, Paijmans, Johanna L. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017230/
https://www.ncbi.nlm.nih.gov/pubmed/31906474
http://dx.doi.org/10.3390/genes11010050