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Consensify: A Method for Generating Pseudohaploid Genome Sequences from Palaeogenomic Datasets with Reduced Error Rates
A standard practise in palaeogenome analysis is the conversion of mapped short read data into pseudohaploid sequences, frequently by selecting a single high-quality nucleotide at random from the stack of mapped reads. This controls for biases due to differential sequencing coverage, but it does not...
Autores principales: | Barlow, Axel, Hartmann, Stefanie, Gonzalez, Javier, Hofreiter, Michael, Paijmans, Johanna L. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017230/ https://www.ncbi.nlm.nih.gov/pubmed/31906474 http://dx.doi.org/10.3390/genes11010050 |
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