The EGFR-TMEM167A-p53 Axis Defines the Aggressiveness of Gliomas

Despite the high frequency of EGFR and TP53 genetic alterations in gliomas, little is known about their crosstalk during tumor progression. Here, we described a mutually exclusive distribution between mutations in these two genes. We found that wild-type p53 gliomas are more aggressive than their mu...

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Detalles Bibliográficos
Autores principales: Segura-Collar, Berta, Gargini, Ricardo, Tovar-Ambel, Elena, Hernández-SanMiguel, Esther, Epifano, Carolina, Pérez de Castro, Ignacio, Hernández-Laín, Aurelio, Casas-Tintó, Sergio, Sánchez-Gómez, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017250/
https://www.ncbi.nlm.nih.gov/pubmed/31947645
http://dx.doi.org/10.3390/cancers12010208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017250/
https://www.ncbi.nlm.nih.gov/pubmed/31947645
http://dx.doi.org/10.3390/cancers12010208

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