Human Tumor–Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing

In vitro cancer drug testing carries a low predictive value. We developed the human leiomyoma–derived matrix “Myogel” to better mimic the human tumor microenvironment (TME). We hypothesized that Myogel could provide an appropriate microenvironment for cancer cells, thereby allowing more in vivo–rele...

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Detalles Bibliográficos
Autores principales: Tuomainen, Katja, Al-Samadi, Ahmed, Potdar, Swapnil, Turunen, Laura, Turunen, Minna, Karhemo, Piia-Riitta, Bergman, Paula, Risteli, Maija, Åström, Pirjo, Tiikkaja, Riia, Grenman, Reidar, Wennerberg, Krister, Monni, Outi, Salo, Tuula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017272/
https://www.ncbi.nlm.nih.gov/pubmed/31905951
http://dx.doi.org/10.3390/cancers12010092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017272/
https://www.ncbi.nlm.nih.gov/pubmed/31905951
http://dx.doi.org/10.3390/cancers12010092

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