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The Immuno-Modulatory Effects of Inhibitor of Apoptosis Protein Antagonists in Cancer Immunotherapy

One of the hallmarks of cancer cells is their ability to evade cell death via apoptosis. The inhibitor of apoptosis proteins (IAPs) are a family of proteins that act to promote cell survival. For this reason, upregulation of IAPs is associated with a number of cancer types as a mechanism of resistan...

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Detalles Bibliográficos
Autores principales: Michie, Jessica, Kearney, Conor J., Hawkins, Edwin D., Silke, John, Oliaro, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017284/
https://www.ncbi.nlm.nih.gov/pubmed/31947615
http://dx.doi.org/10.3390/cells9010207