Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer

Trillium tschonoskii Maxim (TTM), a traditional Chinese medicine, has been demonstrated to have a potent anti-tumor effect. Recently, polyphyllin VI (PPVI), a main saponin isolated from TTM, was reported by us to significantly suppress the proliferation of non-small cell lung cancer (NSCLC) via the...

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Detalles Bibliográficos
Autores principales: Teng, Jin-Feng, Mei, Qi-Bing, Zhou, Xiao-Gang, Tang, Yong, Xiong, Rui, Qiu, Wen-Qiao, Pan, Rong, Law, Betty Yuen-Kwan, Wong, Vincent Kam-Wai, Yu, Chong-Lin, Long, Han-An, Xiao, Xiu-Li, Zhang, Feng, Wu, Jian-Ming, Qin, Da-Lian, Wu, An-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017302/
https://www.ncbi.nlm.nih.gov/pubmed/31941010
http://dx.doi.org/10.3390/cancers12010193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017302/
https://www.ncbi.nlm.nih.gov/pubmed/31941010
http://dx.doi.org/10.3390/cancers12010193

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