Activation of PERK Contributes to Apoptosis and G(2)/M Arrest by Microtubule Disruptors in Human Colorectal Carcinoma Cells

Microtubule-targeting agents (MTAs) are widely used in cancer chemotherapy, but the therapeutic responses significantly vary among different tumor types. Protein kinase RNA-like endoplasmic reticular (ER) kinase (PERK) is an ER stress kinase, and the role of PERK in the anticancer effects of MTAs is...

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Detalles Bibliográficos
Autores principales: Wu, Ming-Shun, Chien, Chih-Chiang, Jargalsaikhan, Ganbolor, Ilsan, Noor Andryan, Chen, Yen-Chou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017320/
https://www.ncbi.nlm.nih.gov/pubmed/31906029
http://dx.doi.org/10.3390/cancers12010097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017320/
https://www.ncbi.nlm.nih.gov/pubmed/31906029
http://dx.doi.org/10.3390/cancers12010097

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