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Activation of PERK Contributes to Apoptosis and G(2)/M Arrest by Microtubule Disruptors in Human Colorectal Carcinoma Cells
Microtubule-targeting agents (MTAs) are widely used in cancer chemotherapy, but the therapeutic responses significantly vary among different tumor types. Protein kinase RNA-like endoplasmic reticular (ER) kinase (PERK) is an ER stress kinase, and the role of PERK in the anticancer effects of MTAs is...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017320/ https://www.ncbi.nlm.nih.gov/pubmed/31906029 http://dx.doi.org/10.3390/cancers12010097 |