Stromal Features of the Primary Tumor Are Not Prognostic in Genetically Engineered Mice of Pancreatic Cancer

The Kras(G12D/+);LSL-Trp53(R172H/+);Pdx-1-Cre (KPC) mouse model is frequently employed for preclinical therapeutic testing, in particular in regard to antistromal therapies. Here, we investigate the prognostic implications of histopathological features that may guide preclinical trial design. Pancre...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasselluhn, Marie C., Klein, Lukas, Patzak, Melanie S., Buchholz, Sören M., Ströbel, Philipp, Ellenrieder, Volker, Maisonneuve, Patrick, Neesse, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017324/
https://www.ncbi.nlm.nih.gov/pubmed/31878349
http://dx.doi.org/10.3390/cells9010058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017324/
https://www.ncbi.nlm.nih.gov/pubmed/31878349
http://dx.doi.org/10.3390/cells9010058

Ejemplares similares