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Mapping DNA Topoisomerase Binding and Cleavage Genome Wide Using Next-Generation Sequencing Techniques

Next-generation sequencing (NGS) platforms have been adapted to generate genome-wide maps and sequence context of binding and cleavage of DNA topoisomerases (topos). Continuous refinements of these techniques have resulted in the acquisition of data with unprecedented depth and resolution, which has...

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Detalles Bibliográficos
Autores principales: McKie, Shannon J., Maxwell, Anthony, Neuman, Keir C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017377/
https://www.ncbi.nlm.nih.gov/pubmed/31941152
http://dx.doi.org/10.3390/genes11010092