Cargando…
Mapping DNA Topoisomerase Binding and Cleavage Genome Wide Using Next-Generation Sequencing Techniques
Next-generation sequencing (NGS) platforms have been adapted to generate genome-wide maps and sequence context of binding and cleavage of DNA topoisomerases (topos). Continuous refinements of these techniques have resulted in the acquisition of data with unprecedented depth and resolution, which has...
Autores principales: | McKie, Shannon J., Maxwell, Anthony, Neuman, Keir C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017377/ https://www.ncbi.nlm.nih.gov/pubmed/31941152 http://dx.doi.org/10.3390/genes11010092 |
Ejemplares similares
-
DNA topoisomerases: Advances in understanding of cellular roles and multi-protein complexes via structure-function analysis
por: McKie, Shannon J., et al.
Publicado: (2021) -
Topoisomerase VI is a chirally-selective, preferential DNA decatenase
por: McKie, Shannon J, et al.
Publicado: (2022) -
Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV
por: Pitts, Steven L., et al.
Publicado: (2011) -
Comparison of DNA decatenation by Escherichia coli topoisomerase IV and topoisomerase III: implications for non-equilibrium topology simplification
por: Seol, Yeonee, et al.
Publicado: (2013) -
Activities of gyrase and topoisomerase IV on positively supercoiled DNA
por: Ashley, Rachel E., et al.
Publicado: (2017)