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Reliability and correlation of mixture cell correction in methylomic and transcriptomic blood data

OBJECTIVES: The number of DNA methylome and RNA transcriptome studies is growing, but investigators have to consider the cell type composition of tissues used. In blood samples, the data reflect the picture of a mixture of different cells. Specialized algorithms can address the cell-type heterogenei...

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Detalles Bibliográficos
Autores principales: Chaumette, Boris, Kebir, Oussama, Dion, Patrick A., Rouleau, Guy A., Krebs, Marie-Odile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017605/
https://www.ncbi.nlm.nih.gov/pubmed/32051015
http://dx.doi.org/10.1186/s13104-020-4936-2